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Cystathionine β-synthase inhibition is a potential therapeutic approach to treatment of ischemic injury

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Hydrogen sulfide (H2S) has been reported to exacerbate stroke outcome in experimental models. Cystathionine β-synthase (CBS) has been implicated as the predominant H2S-producing enzyme in central nervous system. When SH-SY5Y cells were transfected to overexpr... ...