Probing residues in the pore-forming (M2) domain of the Cys-loop receptor homologue GLIC reveals some unusual features
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Cys-loop receptors play important roles in signal transduction. The Gloeobacter ligand-gated ion channel (GLIC) pore binds similar compounds to Cys-loop receptor pores, but has the advantage of known structures in open and closed states. GLIC is activated by p... ...
