F508del-cystic fibrosis transmembrane regulator correctors for treatment of cystic fibrosis: a patent review
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Introduction: Cystic fibrosis (CF) is an autosomal recessive genetic disease caused by malfunction of CF transmembrane regulator (CFTR). The deletion of a phenylalanine at residue 508 (F508del) is the most common mutation that ca... ...
