Tumor-specific expression of HMG-CoA reductase in a population-based cohort of breast cancer patients
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Background: The mevalonate pathway synthetizes cholesterol, steroid hormones, and non-steriod isoprenoids necessary for cell survival. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) is the rate-limiting enzyme of the mev... ...
