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Chondroprotective Effects of Wogonin in Experimental Models of Osteoarthritis in vitro and in vivo

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We evaluated the chondroprotective effects of wogonin by investigating its effects on the gene expression and production of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as on production of MMP-3 in the rat knee.... ...