Germline polymorphisms in genes involved in the Hippo pathway as recurrence biomarkers in stages II/III colon cancer
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The Hippo pathway regulates tissue growth and cell fate. In colon cancer, Hippo pathway deregulation promotes cellular quiescence and resistance to 5-Fluorouracil (5-Fu). In this study, 14 polymorphisms in 8 genes involved in the Hippo pathway (MST1, MST2, LAT... ...