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Indoleamine 2,3 Dioxygenase as a Potential Therapeutic Target in Huntington's Disease

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Within the past decade, there has been increasing interest in the role of tryptophan (Trp) metabolites and the kynurenine pathway (KP) in diseases of the brain such as Huntington's disease (HD). Evidence is accumulating to suggest that this pathway is imbalanc... ...