A comprehensive functional and clinical analysis of ABCC2 and its impact on treatment response to carbamazepine
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At the blood-brain barrier, overexpression of the drug efflux transporter ABCC2 (also known as MRP2) has been proposed as a mechanism for impaired carbamazepine (CBZ) treatment response in epilepsy. However, investigation of the impact of ABCC2 polymorphisms o... ...
