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In vitro Activation of heme oxygenase-2 by menadione and its analogs

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Background: Previously, we reported that menadione activated rat, native heme oxygenase-2 (HO-2) and human recombinant heme oxygenase-2 selectively; it did not activate spleen, microsomal heme oxygenase-1. The purpose of this stu... ...