In-silico analysis for RNA-interference mechanism of α-synuclein to treat Parkinson's disease
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Parkinson's Disease (PD) causing mutations in α-synuclein gene are ALA30PRO, GLU46LYS and ALA53THR. The conformational changes in proteins with respect to all the three mutations were analysed. These were used to predict the structures of Short Interfering RN... ...
