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Evaluation of WO2013076170: the use of a dihydroorotate dehydrogenase inhibitor for the treatment of psoriasis

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Inhibition of dihydroorotate dehydrogenase (DHODH) modulates pyrimidine biosynthesis. Effective inhibitors are immunomodulatory drugs clinically useful in the treatment of diseases such as rheumatoid arthritis, psoriatic arthritis and multiple sclerosis. There... ...