Differences in recognition of wild-type and lipoprotein-deficient strains of oral Streptococci in vitro and in vivo
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Whole cells of wild-type strains of Streptococcus gordonii and Streptococcus mutans induced Toll-like receptor 2 (TLR2)-mediated nuclear factor-κB (NF-κB) activation, whereas those of lipoprotein (LP)-deficient strains did not. All strains upregulated the pr... ...