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bi-3-azaoxoisoaporphine derivatives have antidepressive properties in a murine model of post stroke-depressive like behavior

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In the present study, three bi-3-azaoxoisoaporphine derivatives were synthesized and intracerebroventricularly administrated to BALB/c mice. The antidepressant actions in stroke-induced depressive like behavior in mice were examined using despair swimming test... ...