Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST
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The genetic mechanisms involved in the transformation from a benign neurofibroma to a malignant sarcoma in patients with neurofibromatosis-type-1- (NF1-)associated or sporadic malignant peripheral nerve sheath tumors (MPNSTs) remain unclear. It is hypothesized... ...
