PAI-1 and IFN-γ in the regulation of innate immune homeostasis during sublethal yersiniosis
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Plasminogen activator inhibitor type 1 (PAI-l), a key part of the fibrinolytic system, plays a critical host protective role during the acute phase of infection by regulating interferon(IFN)-γ release. IFN-γ regulates PAI-1 expression, which suggests an intr... ...