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Biophysical assessment of DC iontophoresis and current density on transdermal permeation of methotrexate

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Introduction: The effect of DC iontophoresis using low (0.2 mA/cm(2)) and high current density (0.5 mA/cm(2)) on transdermal permeation of methotrexate loaded into polyacrylamide hydrogel patch was investigated. ... ...