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Intravenous infusion of hyperosmotic NaCl solution induces acute cor pulmonale in anesthetized rats

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Intravenous hyperosmotic NaCl infusion is an effective treatment for circulatory shock. However, a fast infusion rate (2 mL/kg at the rate of 1 mL/s) induces transient hypotension. This response has been reported to be due to decreased total peripheral resista... ...