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Parasite (Paris, France). 2012 Aug;19(3):249-57. doi: 10.1051/parasite/2012193249 Q22.42025

Immunosuppression with cyclophosphamide favors reinfection with recombinant Toxoplasma gondii strains

环磷酰胺诱导的免疫抑制有利于重组子胎盘球虫再感染 翻译改进

L A Silva  1, G P Brandão, B V Pinheiro, R W A Vitor

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  • 1 Departamento de Parasitologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais (UFMG), Av. Antonio Carlos 6627, 31270-901, Belo Horizonte, MG, Brazil.
  • DOI: 10.1051/parasite/2012193249 PMID: 22910667

    摘要 Ai翻译

    The aim of this study was to verify the effect of immunosuppression by cyclophosphamide (Cy) on susceptibility of BALB/c mice subjected to challenge with recombinant strains of Toxoplasma gondii. Animals were prime infected with the D8 (recombinant I/III) or the ME49 (type II) non-virulent strains, weekly immunosuppressed with Cy and challenged with the CH3 or EGS virulent strains (I/III). Parasites recovered from surviving mice were submitted to PCR-RFLP ... ...点击完成人机验证后继续浏览
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    期刊名:Parasite

    缩写:PARASITE

    ISSN:1252-607X

    e-ISSN:1776-1042

    IF/分区:2.4/Q2

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    Immunosuppression with cyclophosphamide favors reinfection with recombinant Toxoplasma gondii strains