Deletion of endoplasmic reticulum stress-induced CHOP protects microvasculature post-spinal cord injury
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Trauma introduces damaging stressors that compromise protein, lipid, and nucleic acid integrity. Aggregates of unfolded and misfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response (ERSR)/unfolded protein response (UPR) leading to a... ...
