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Activation of the ERK 1/2 and STAT3 signaling pathways is required for 661W cell survival following oxidant injury

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Aim: To evaluate the influence of hydrogen peroxide (H(2)O(2)) on mouse photoreceptor-derived 661W cell survival and to determine the effect of PD98059, an inhibitor for MEK1 (the direct upstream activator of ERK1/2), and S3I201,... ...