The extent of cardiac myosin binding protein-C phosphorylation modulates actomyosin function in a graded manner
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Cardiac myosin binding protein-C (cMyBP-C), a sarcomeric protein with 11 domains, C0-C10, binds to the myosin rod via its C-terminus, while its N-terminus binds regions of the myosin head and actin. These N-terminal interactions can be attenuated by phosphoryl... ...
