Synthesis and anti-proliferative activity of substituted-anilinoquinazolines and its relation to EGFR inhibition
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4-Anilinoquinazoline is a privileged scaffold in developing small molecule inhibitors of tyrosine kinases (TK) especially epidermal growth factor receptor (EGFR). 2 series belonging to 3'-substituted-4-anilinoquinazoline scaffold were synthesized and screened ... ...