Bicc1 links the regulation of cAMP signaling in polycystic kidneys to microRNA-induced gene silencing
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Genetic defects in autosomal-dominant polycystic kidney disease (ADPKD) promote cystic growth of renal tubules, at least in part by stimulating the accumulation of cAMP. How renal cAMP levels are regulated is incompletely understood. We show that cAMP and the ... ...