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Short-term high-dose effect of lovastatin on thrombolysis by rt-PA in a human whole-blood in vitro clot model

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High-dose hydroxymethylglutaryl coenzyme. A reductase inhibitor (statin) administration reduces neuronal injury and improves outcomes in experimental models of acute ischemic stroke, and has been shown to be safe in a phase 1 dose-escalation study using lovast... ...