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Hypothetical two-step initiation of experimental carcinogenesis by polycyclic aromatic hydrocarbons and aminoazo dyes

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A new hypothesis is discussed, which describes the initiation of the carcinogenesis through polycyclic aromatic hydrocarbons (PAHs) and aminoazo dyes (AZOs) as a two-step process: the oncogenic proteins of the ras or ras-like on-cogenes activated by mutation (... ...