Comparative Study of Cyanobacterial and E. coli RNA Polymerases: Misincorporation, Abortive Transcription, and Dependence on Divalent Cations
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If Mg(2+) ion is replaced by Mn(2+) ion, RNA polymerase tends to misincorporate noncognate nucleotide, which is thought to be one of the reasons for the toxicity of Mn(2+) ion. Therefore, most cells have Mn(2+) ion at low intracellular concentrations, but cyan... ...