The conformational flexibility of the C-terminus of histone H4 promotes histone octamer and nucleosome stability and yeast viability
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Background: The protein anti-silencing function 1 (Asf1) chaperones histones H3/H4 for assembly into nucleosomes every cell cycle as well as during DNA transcription and repair. Asf1 interacts directly with H4 through the C-termi... ...