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Trastuzumab for HER2-Positive Metastatic Breast Cancer: Clinical and Economic Considerations

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Trastuzumab is a recombinant humanized monoclonal antibody that selectively targets the extra-cellular domain of the HER2 receptor. It was approved by the FDA in September 1998 as the first targeted therapy for HER2-positive metastatic breast cancer, and has s... ...