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Suppressed hepcidin expression correlates with hypotransferrinemia in copper-deficient rat pups but not dams

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Copper deficiency leads to anemia but the mechanism is unknown. Copper deficiency also leads to hypoferremia, which may limit erythropoiesis. The hypoferremia may be due to limited function of multicopper oxidases (MCO) hephaestin in enterocytes or GPI-cerulop... ...