Toll-like receptors in ischaemia and its potential role in the pathophysiology of muscle damage in critical limb ischaemia
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Toll-like receptors (TLRs) are key receptors of the innate immune system which are expressed on immune and nonimmune cells. They are activated by both pathogen-associated molecular patterns and endogenous ligands. Activation of TLRs culminates in the release o... ...
