A new look at glutamate and ischemia: NMDA agonist improves long-term functional outcome in a rat model of stroke
{{output}}
Ischemic stroke triggers a massive, although transient, glutamate efflux and excessive activation of NMDA receptors (NMDARs), possibly leading to neuronal death. However, multiple clinical trials with NMDA antagonists failed to improve, or even worsened, strok... ...
