Exaggerated NMDA mediated LTD in a mouse model of Down syndrome and pharmacological rescuing by memantine
{{output}}
The Ts65Dn mouse is the best-studied animal model for Down syndrome. In the experiments described here, NMDA-mediated or mGluR-mediated LTD was induced in the CA1 region of hippocampal slices from Ts65Dn and euploid control mice by bath application of 20 µM N... ...
