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Amylin analogues in the treatment of diabetes mellitus: medicinal chemistry and structural basis of its function

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Amylin, (islet amyloid polypeptide) or diabetes-associated peptide is co-secreted with insulin in the islet of Langerhans of diabetic patients in approximately 1:100, amylin-insulin ratio. The soluble form of amylin, an analogue of amylin, is used as a supplem... ...