Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy
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In the recent years, the discovery of a series of mutations in patients with myeloid malignancies has provided insight into the pathogenesis of myelodysplastic syndromes (MDSs), myeloproliferative neoplasms (MPNs), and acute myeloid leukemia (AML). Among these... ...
