Structural and Functional Analysis of the Complex between Citrate and the Zinc Peptidase Carboxypeptidase A
{{output}}
A high-resolution carboxypeptidase-Zn(2+)-citrate complex was studied by X-ray diffraction and enzyme kinetics for the first time. The citrate molecule acts as a competitive inhibitor of this benchmark zinc-dependent peptidase, chelating the catalytic zinc ion... ...
