Selective inactivation of adenosine A(2A) receptors in striatal neurons enhances working memory and reversal learning
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The adenosine A(2A) receptor (A(2A)R) is highly enriched in the striatum where it is uniquely positioned to integrate dopaminergic, glutamatergic, and other signals to modulate cognition. Although previous studies support the hypothesis that A(2A)R inactivatio... ...