Activation of human platelets by 2-arachidonoylglycerol: role of PKC in NO/cGMP pathway modulation
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We demonstrated that the endocannabinoid 2-arachidonoylglycerol (2-AG) activated dose-dependently washed human platelets and increased intracellular calcium levels. Moreover 2-AG activated protein kinase C measured as p47pleckstrin phosphorylation. These param... ...