MicroRNAs 130a/b are regulated by BCR-ABL and downregulate expression of CCN3 in CML
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Chronic Myeloid Leukaemia (CML) is a myeloproliferative disorder characterized by the expression of the oncoprotein, Bcr-Abl kinase. CCN3 normally functions as a negative growth regulator, but it is downregulated in CML, the mechanism of which is not known. Mi... ...
