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Invariant NKT Cell Lines Derived from the NOD·H2 Mouse Enhance Autoimmune Thyroiditis

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To study the role of invariant Natural Killer T cell ( iNKT) cells in autoimmune thyroiditis, we derived two iNKT cell lines from the spleens of NOD· H2(h4) mice, a strain that develops spontaneous autoimmune thyroiditis exacerbated by excess dietary iodine. ... ...