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Deficient NRG1-ERBB signaling alters social approach: relevance to genetic mouse models of schizophrenia

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Growth factor Neuregulin 1 (NRG1) plays an essential role in development and organization of the cerebral cortex. NRG1 and its receptors, ERBB3 and ERBB4, have been implicated in genetic susceptibility for schizophrenia. Disease symptoms include asociality and... ...