Synthesis, characterization, and in vitro drug release study of methacrylate diclofenac conjugate as macromolecular prodrug
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Diclofenac was covalently coupled to 2-hydroxyl ethyl methacrylate (HEMA) to get a monomeric drug derivative of diclofenac. This monomer was subjected to radicular polymerization to get poly(diclo-EMA) conjugate. The in vitro drug release study of the polymeri... ...
