Establishment and characterization of Prnp knockdown neuroblastoma cells using dual microRNA-mediated RNA interference
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Prion diseases are fatal transmissible neurodegenerative disorders. In the pathogenesis of the disease, the cellular prion protein (PrPC) is required for replication of abnormal prion (PrPSc), which results in accumulation of PrPSc. Although there have been ex... ...
