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Trichostatin A modulates apoptotic-related gene expression and improves embryo viability in cloned bovine embryos

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Low efficiency of somatic cell nuclear transfer (SCNT) is attributed to incomplete reprogramming of transferred nuclei into oocytes. Trichostatin A (TSA), a histone deacetylase inhibitor, has been used to enhance nuclear reprogramming following SCNT. However, ... ...