The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1
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DMF (dimethyl fumarate) exerts anti-inflammatory and pro-metabolic effects in a variety of cell types, and a formulation (BG-12) is being evaluated for monotherapy in multiple sclerosis patients. DMF modifies glutathione (GSH) levels that can induce expression... ...
