Association of genetic polymorphisms of CYP 2C19 with hypertension in a Chinese Han population
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Objectives: Cytochrome P450 (CYP) 2C19 is expressed in vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which play a centralrole in regulating renal tubular fluid-elec... ...