Infrequent hypermethylation of WIF-1 promoter in BCR/ABL-negative myeloproliferative disorders
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Objective: The Wnt/β;-catenin signaling pathway is important in the pathogenesis of hematological malignancies. Wnt inhibitory factor-1 (WIF-1) is a negative regulator of Wnt signaling that is frequently downregulated by hyperme... ...
