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Bicuspid aortic valve disease: the role of oxidative stress in Lrp5 bone formation

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The bicuspid aortic valve is a common congenital cardiac anomaly, having a prevalence of 0.9% to 1.37% in the general population and a male preponderance ratio of 2:1. The recognition of a bicuspid aortic valve is clinically relevant because of its association... ...