Design of anti-parasitic and anti-fungal hydroxy-naphthoquinones that are less susceptible to drug resistance
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Atovaquone is a hydroxy-naphthoquinone that is used to treat parasitic and fungal infections including Plasmodium falciparum (malaria), Pneumocystis jivorecii (pneumonia) and Toxoplasma gondii (toxoplasmosis). It blocks mitochondrial oxidation of ubiquinol in ... ...
