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Protective effects of manganese(II) chloride on hyaluronan degradation by oxidative system ascorbate plus cupric chloride

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The degradation of several high-molar-mass hyaluronan samples was investigated in the presence of ascorbic acid itself and further by an oxidative system composed of ascorbic acid plus transition metal ions, i.e. Fe(II) or Cu(II) ions. The latter oxidative sys... ...