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5-androstenediol ameliorates pleurisy, septic shock, and experimental autoimmune encephalomyelitis in mice

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Androstenediol (androst-5-ene-3β,17β-diol; 5-AED), a natural adrenal steroid, has been shown to suppress experimental autoimmune encephalomyelitis (EAE) in female SJL/J mice. We here report that 5-AED limits inflammation and proinflammatory cytokines includi... ...